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1-Naphthohydroxamic acid

Glpbio

Catalog No：GC39214-10mM (in 1mL DMSO) CAS No.：6953-61-3 MDLNo： Brand:Glpbio purity： 特性： Purpose:1-Naphthohydroxamic acid (Compound 2) 是一种有效的，选择性的 HDAC8 抑制剂，IC50 为 14 μM。1-Naphthohydroxamic acid 对 HDAC8 的选择性高于 I 类 HDAC1 和 II 类 HDAC6 (IC50 100 μM)。1-Naphthohydroxamic acid 不会增加整体组蛋白 H4 的乙酰化，也不会降低总细胞内 HDAC 的活性。1-Naphthohydroxamic acid 可诱导微管蛋白乙酰化。DMSO: 125 mg/mL (667.77 mM)

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Product Overview

Product Name	1-Naphthohydroxamic acid
CAS	6953-61-3
Formula	C₁₁H₉NO₂
MW	187.19
Storage condition	Store at -20°C

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